PerfWeb 25 Acute Kidney Injury (AKI). Drivers Of Urine Production
PerfWeb 25 Acute Kidney Injury (AKI). Drivers Of Urine Production

PerfWeb 25 Acute Kidney Injury (AKI). Drivers Of Urine Production

  • Faculty: John Ingram, CCP
  • Date: August 10th, 2019 12:00 am
  • CEU’s: 0.84 CEUs
  • Price: $12.6
  • Category 1 SDCE CEU
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Course description

The learner will be able to describe the physiologic principles of urine production and discuss how cardiopulmonary bypass effects urine production and the potential development of Acute Kidney Injury (AKI). Urine Production. Renal Anatomy. What is Acute Kidney Injury?


In a highly informative and engaging video presentation, John Ingram delves into the intricate mechanisms that drive urine production, particularly focusing on Acute Kidney Injury (AKI). Ingram's talk is a blend of medical science, physiology, and practical insights aimed at healthcare providers, students, and anyone interested in understanding the complexities of renal function. This video is a sequel to a previous presentation and forms part of the esteemed PerfWeb series.

Objectives and Focus

The primary objective of the talk is to elucidate the key drivers of urine production, especially as it relates to AKI. Ingram explores the role of various hormones, receptors, and physiological pathways that contribute to urine production and, by extension, the maintenance of renal health. This discussion is vital in the context of AKI, where an imbalance in these mechanisms can lead to severe medical complications.

Hormonal Interplay

Ingram delves into the role of critical hormones such as renin, aldosterone, and antidiuretic hormone (ADH) in regulating urine production. He explains how changes in blood pressure and blood volume affect the secretion of these hormones, which in turn impacts renal function. The talk also touches upon the role of angiotensin II, emphasizing its vasoconstrictive properties and its impact on renal blood flow.

Receptors and Feedback Mechanisms

A significant portion of the talk is dedicated to explaining the role of various receptors, including baroreceptors and atrial stretch receptors, in sensing changes in blood pressure and volume. Ingram discusses the delicate balance and "tug-of-war" between these receptors and how they influence renal function through complex feedback mechanisms.

Clinical Implications

Ingram provides real-world examples and case studies to showcase the clinical implications of the physiological mechanisms he describes. He highlights how understanding these drivers of urine production is essential for clinicians who deal with cases of AKI, hypertension, and other renal-related conditions. The talk also offers practical guidelines for medical interventions, discussing how various therapeutic approaches can affect renal function.

Takeaways and Future Directions

The video closes with a summary slide that encapsulates the core messages of the talk and emphasizes the need for further research and understanding of the topic. Ingram humbly admits that despite his extensive knowledge, the field is vast, and there is much to learn.

Relevance and Consistency

What sets this video apart is its consistent theme and its relevance to ongoing medical debates and research. Ingram's presentation fits well into the broader scope of the PerfWeb series, making it a must-watch for anyone interested in renal physiology and pathology.


John Ingram's talk on the drivers of urine production and its relation to Acute Kidney Injury is a tour de force in medical education. It combines scientific depth with practical insights, making it an invaluable resource for healthcare providers and students alike. Whether you're a seasoned medical professional or a curious learner, this video offers a deep dive into the mechanisms that underlie one of the body's most vital functions—urine production. The insights gained from this presentation not only deepen our understanding of renal physiology but also have profound implications for the diagnosis and treatment of Acute Kidney Injury and other renal disorders.

This video is not just a lecture; it's a call to action for deeper understanding and research into a topic that holds significant medical importance. Don't miss out on this opportunity to expand your knowledge and perspective on renal function and Acute Kidney Injury.

Meet Your Instructor

John Ingram, CCP

John Ingram, CCP

John Ingram is a magna cum laude graduate from University of Texas, Texas Heart Institute and a board certified perfusionist currently specializing in adult perfusion

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