TransCatheter Valve Replacement (TAVR) and SAVR-Update on Outcome
TransCatheter Valve Replacement (TAVR) and SAVR-Update on Outcome

TransCatheter Valve Replacement (TAVR) and SAVR-Update on Outcome

  • Faculty: Prakash Balan, MD
  • Date: August 5th, 2019 1:00 pm
  • CEU’s: 0.48 CEUs
  • Price: $7.2
  • Category 1 SDCE CEU
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Course description

Dr. Prakash Balan lectures and discusses the latest outcomes data on TransCatheter Valve Replacement (TAVR) Vs. Surgical Aortic Valve Replacement (SAVR) 

Dr. Balan presents several case studies and engages in lively debate about patient selection, over use, and presents his views in support of TAVR as a first line option for patients in the low risk group. 

Advances in Aortic Valve Replacement: TAVR vs. SAVR Outcomes Update

The landscape of aortic valve replacement has undergone significant transformation with the advent of Transcatheter Aortic Valve Replacement (TAVR), especially for patients across various surgical risk categories. This video provides an in-depth analysis of the outcomes and technological advancements in TAVR compared to traditional Surgical Aortic Valve Replacement (SAVR), offering critical insights for perfusionists engaged in these procedures.

Introduction to TAVR and SAVR

The session begins with a historical overview of TAVR's development over the past decade, describing it as a maturation of transformational technology initially focused on patients ineligible for surgery. The evolution of TAVR is highlighted through a series of clinical trials, demonstrating its efficacy and safety, which now positions it as a less invasive alternative to SAVR, even for patients with lower surgical risk.

Key Clinical Trials and Their Impact

The video outlines six significant clinical trials that have progressively demonstrated TAVR’s applicability to broader patient groups—from high-risk to low-risk individuals. These trials include the PARTNER trials and the CoreValve trials, each contributing to the robust evidence supporting the use of TAVR in different risk stratifications.

Technological Progressions in Valve Designs

Significant advancements in TAVR device technology are discussed, emphasizing the enhancements from earlier designs like the SAPIEN valve to newer iterations such as the SAPIEN 3 and various CoreValve models. These improvements have not only reduced procedural risks but also enhanced patient outcomes by minimizing complications such as paravalvular leakage.

Detailed Analysis of Surgical Risk Continuum

The presentation delves into the shift from high to low surgical risk patient groups, detailing how TAVR has become a viable option across the board. It discusses the criteria used in trials, such as the STS score, and how these criteria determine patient eligibility and expected outcomes in both TAVR and SAVR procedures.

Comparison of TAVR and SAVR Outcomes

A comprehensive comparison of recent trial results, including the PARTNER 3 trial and the CoreValve Low-Risk trial, is provided. These trials have shown that TAVR not only competes with but in many cases, surpasses SAVR in terms of efficacy, with lower rates of disabling strokes and re-hospitalizations, marking a significant shift in treatment paradigms.

Future Directions and Clinical Implications

The video concludes with a forward-looking perspective on the implications of these findings for clinical practice. It discusses ongoing research and potential future innovations in valve technology and procedural techniques. The role of the heart team, including perfusionists, in deciding the optimal intervention for each patient is emphasized, ensuring a personalized approach to aortic valve replacement.


This presentation is an invaluable resource for perfusionists and other cardiac care professionals, providing them with a detailed understanding of the current state and future potential of aortic valve replacement therapies. It underscores the importance of staying updated with technological and clinical developments to enhance patient care and outcomes in cardiac surgery settings.

#perfusion #TAVR #SAVR 
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Meet Your Instructor

Prakash Balan, MD

Prakash Balan, MD

Dr. Prakash Balan is a board certified Physician and Assistant Professor for the Department of Internal Medicine at McGovern Medical School at The University of Texas Health Science Center

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